Expanded Access Program for Asfotase Alfa Treatment for Patients With Infantile- or Juvenile-onset Hypophosphatasia (HPP)

Study Identifier:
AA-HPP-405
ClinicalTrials.gov Identifier:
EudraCT Identifier:
N/A
Sponsor:
Alexion Pharmaceuticals, Inc.
Study Contact Information:
N/A
Other

Study Details

Medical Condition
  • Unmapped
Study Drug
  • Biological: asfotase alfa
Date
N/A - N/A
Phase 1
Phase 2
Phase 3
Phase 4
N/A
Patient Requirements
Sex: Female & Male
Age: N/A - N/A
Requirements Information
Sex
Female & Male
Age
N/A - N/A

Study Details

Medical Condition
  • Unmapped
Study Drug
  • Biological: asfotase alfa
Date
N/A - N/A
Phase 1
Phase 2
Phase 3
Phase 4
N/A
Patient Requirements
Sex: Female & Male
Age: N/A - N/A years
Requirements Information

Protocol Summary

This clinical trial is being conducted in Hypophosphatasia, a bone disorder caused by gene mutation(s) resulting in bone defects. These gene mutations cause low levels of an enzyme needed to harden bone. The purpose of this study is to provide access to treatment in a disease where no approved treatment exists. This is an experimental treatment provided under specific treatment guidelines in which safety endpoints will be collected.

Trial Locations

Location
Status
Location
Colorado Center for Bone Research
Lakewood, Colorado, United States, 80227
Status
N/A
Location
Children's Hospital of Pittsburgh
Pittsburgh, Pennsylvania, United States, 15224
Status
N/A
Location
Hôpital Bicêtre
Le Kremlin-Bicêtre, France, 94275
Status
N/A
Location
Hôpital Necker - Enfants Malades
Paris, France, 75015
Status
N/A
Location
Hôpital des Enfants
Toulouse Cedex 9, France, 31259
Status
N/A